This integrated experimental and computational study elucidates the mechanisms that contribute to the novel properties of Al/a-Si CSNs and characterizes the tribological properties of surface composed of these nanostructures, which provides a foundation for the rational design of novel technologies based on CSNs. In this thesis, we developed coreshell nanoparticles (CSNPs) with finely tuned silica shell on iron oxide core as model system for advanced applications in. In comparison, (100) Si has substantially higher adhesion and COF (~10 μN and ~0.062, respectively), while the Al nanodots have both higher friction (COF ~0.044) and are deformed when subjected to contact loads as low as 250 μN. NSTSs have a coefficient of friction (COF) as low as 0.015, exhibit low adhesion with adhesion forces on the order of less than 1 μN, and are highly deformation resistant, with no apparent surface deformation after nanoscratch testing, even at contact forces up to 8000 μN. Nanostructure-textured surfaces (NSTSs) composed of Al/a-Si CSNs have improved tribological properties compared surfaces patterned with Al nanodots and a flat (100) Si surface. Furthermore, dislocations nucleated in the core of core-shell nanorods are not as effectively removed as compared to CSNs. Smaller core diameters correlate with the development of a larger back-stress within the core during unloading, which further correlates with improved dislocation annihilation after unloading. The Synthesis of Core-Shell IronGold Nanoparticles and Their. You may use this material in any way that is permitted by. As the core confinement is reduced, either through an increase in confined core volume or a change in the geometrical confinement, the indentation signatures and deformation resistance are significantly reduced.Ĭomplimentary molecular dynamics simulations show that a substantial amount of dislocation egression occurs in the core of CSNs during unloading as dislocations annihilate at the core/shell interface. University of Calgary graduate students retain copyright ownership and moral rights for their thesis. This behavior is attributed to dislocation nucleation and annihilation events enabled by the 3-dimensional confinement of the Al core. In conjunction with the indentation signatures, nearly complete deformation recovery is observed. Core-shell palladium-titanium dioxide NPs, PdTiO, were prepared using. Nanoindentation measurements revealed a unique mechanical response characterized by discontinuous signatures in the load-displacement data. Titanium dioxide nanoparticles (NPs) and iridium(III) complexes have been. Most notably, these nanostructures exhibit substantial deformation recovery, even when loaded much beyond the elastic limit. This spatiotemporally controllable system could provide a new option and era for tumor targeted therapy in the future.Al/a-Si core-shell nanostructures (CSNs), consisting of a hemispherical Al core surrounded by a hard shell of a-Si, have been shown to display unusual mechanical behavior in response to compression loading. THE SYNTHESIS OF CORE-SHELL IRONGOLD NANOPARTICLES AND THEIR CHARACTERIZATION A Thesis Submitted to the Graduate Faculty of the University of New Orleans in partial fulfillment of the requirements for the degree of Master of Science in The Department of Chemistry by Zhihui Ban B.S. In the first third of this thesis, magnetic core gold shell nanoparticles are incorporated into a novel platform for the delivery of a potent anti-cancer. Tumor cell selective cytotoxicity assay in vitro as well as tumor bearing mouse experiments in vivo demonstrated the effective photothermal and NO based chemical synergistic tumor targeted therapy. Meanwhile, responding to NIR as well as the generated heat, the S-nitrosothiol polymeric shells would give off free NO at high concentration, inducing NO based chemotherapy. This thesis focuses on core/shell nanoparticle catalysts including preparation, characterization and testing performance using direct methanol fuel cell. Triggered by near-infrared irradiation (NIR), the Ag core nanoparticle would convert the light to cytotoxic heat via a surface plasmon resonance mechanism for cancer cell apoptosis. Magnetic iron oxide core-shell nanoparticles, coated with a protective. Herein, for the first time, we designed and synthesized hyaluronic acid (HA) modified S-nitrosothiol core–shell nanoparticles for synergistic tumor cell targeted therapy based on photothermal therapy (PTT) and nitric oxide (NO) based chemotherapy. Independent Project in Chemistry Bachelor thesis 15 hec First cycle,G2E. In such a case, it is necessary to develop synergistic therapy strategies. In an attempt to find an effective cancer therapy, nanotherapeutics comes onto the scene as a new therapeutic approach, which is emerging both nanotechnology. Along with the development of controlled delivery systems for targeted therapy, ‘single-strategy’ therapy often fails to achieve the desired performance in real body internal environments.
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